History and possible effects of Arylcyclohexylamines

Phencyclidine (PCP) is believed to be the first arylcyclohexylamine with recognized anesthetic properties, but several arylcyclohexylamines were described before PCP in the scientific literature, beginning with PCA (1-phenylcyclohexan-1-amine) the synthesis of which was first published in 1907. PCE was reported in 1953 and PCMo (4-(1-phenyl-cyclohexyl)-morpholine) in 1954, with PCMo described as a potent sedative. Arylcyclohexylamine anesthetics were intensively investigated at Parke-Davis, beginning with the 1956 synthesis of phencyclidine and later the related compound ketamine. The 1970s saw the debut of these compounds, especially PCP and its analogues, as illicitly used recreational drugs due to their dissociative hallucinogenic and euphoriant effects. Since that time, the class has been expanded by scientific research into stimulant, analgesic, and neuroprotective agents, and also by clandestine chemists in search of novel recreational drugs.

Structure of Arylcyclohexylamines

An arylcyclohexylamine is composed of a cyclohexylamine unit with an aryl moiety attachment. The aryl group is positioned geminal to the amine. In the simplest cases, the aryl moiety is typically a phenyl ring, sometimes with additional substitution. The amine is usually not primary; secondary amines such as methylamino or ethylamino, or tertiary cycloalkylamines such as piperidino and pyrrolidino, are the most commonly encountered N-substituents.

Arylcyclohexylamines properties

You can buy Arylcyclohexilamines online through our shop, RareChems, in powder, blotter or pellet form for research purposes like Neuro-dissociative disorders or where the perception of reality could be affected by the subject. Also, another domain of investigation could be the treatment of inflammatory diseases, specially the chronic ones, and where the central nervous system could be affected causing discomfort or even pain. On the other hand, as substances with interaction with the NMDA receptors and dopamine, arylcyclohexylamines can be used in research of identity disorders and neurodegenerative diseases. However, despite the fact that these properties are in general terms, we encourage to study chemical by chemical, since the interaction with receptors and other neurotransmitters can be different between them.

Special terms and conditions to buy Arylcyclohexylamines

All our research chemicals, including Arylcyclohexylamines, are strictly sold for laboratory and analytic purposes only. If you purchase our offered products from outside of the Netherlands, please check the legal status in your country before ordering since you’re responsible for compliance with the laws of your jurisdiction. If you want to be sure a research chemical of the Arylcyclohexilamine family is available for your country, please read the product description. Another way would be to create an account with us and insert your shipping address in your account. That way, if the product is blocked for your country, the system won’t allow you to add it to your cart. Depending on the country of destination, you’ll have the option to select the airmail shipping method and the registered airmail one, which is trackable and it’s insured by us in the case of lost. Also, the payment method depends on the country of destination, where you should be able to pay using cryptocurrencies like Bitcoin, Litecoin, Ethereum and Monero between others, and by bank transfer in some cases. Once we receive the payment, your order with Arylcyclohexylamines will be set to accepted and we will send you a new email notification. If the payment is received before 16h (CET), your order will be dispatched the next day. You can find more info in the wikipedia page. Note: Some products related to this category might be provided in pellet and/or blotter form only, and therefore not listed under this category. Please check the BLOTTER and PELLET categories as well.